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| Registros recuperados: 43 | |
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| Ky, Chin-long; Barre, Philippe; Noirot, Michel. |
| The objective of the paper was to identify the number of major loci explaining caffeine content in coffee seeds. Investigations were based on previously published results: (1) Caffeine binds to chlorogenic acids in a 1:1 molecular ratio; (2) Between species, the caffeine content is correlated to the chlorogenic acid content; (3) Only a part of chlorogenic acids is bound to caffeine. Especially, the content ratio between caffeine and chlorogenic acids varied between species. For identifying the number of major loci, a quantitative trait locus (QTL) approach was carried out using an interspecific cross between two highly differentiated species-Coffea liberica dewevrei and Coffea pseudozanguebariae, the latter being a caffeine-free species. As main finding,... |
| Tipo: Text |
Palavras-chave: Coffea; Chlorogenic acids; Caffeine; QTL; Interspecific cross. |
| Ano: 2013 |
URL: http://archimer.ifremer.fr/doc/00152/26298/24429.pdf |
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| Gomes,Júlia Ariana de Souza; Faria,Bruno Generoso; Silva,Viviam de Oliveira; Zangerônimo,Márcio Gilberto; Miranda,José Rafael; Lima,Adriene Ribeiro de; Pereira,Rosemary Gualberto Fonseca Alvarenga; Pereira,Luciano José. |
| The objective of this study was to evaluate the influence of integral and decaffeinated coffee brews (Coffea arabica L and C. canephora Pierre) on the metabolic parameters of rats fed with hyperlipidemic diet. Thirty male Wistar rats (initial weight of 270 g ± 20 g) were used in the study, which were divided into six groups five each. The treatments were normal diet, hyperlipidemic diet, hyperlipidemic diet associated with integral coffee arabica or canephora brews (7.2 mL/kg/day) and hyperlipidemic diet associated to decaffeinated arabica, or canephora brews, using the same dosage. After 41 days, performance analyses were conducted.The rats were then euthanized and the carcasses were used for the analysis of dried ether extract and crude protein.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lipids; Adipocytes; Hyperlipidemia; Caffeine; Decaffeination. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000500015 |
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| Bassani,R.A.; Bassani,J.W.M.. |
| Relaxation in the mammalian ventricle is initiated by Ca2+ removal from the cytosol, which is performed by three main transport systems: sarcoplasmic reticulum Ca2+-ATPase (SR-A), Na+-Ca2+ exchanger (NCX) and the so-called slow mechanisms (sarcolemmal Ca2+-ATPase and mitochondrial Ca2+ uptake). To estimate the relative contribution of each system to twitch relaxation, SR Ca2+ accumulation must be selectively inhibited, usually by the application of high caffeine concentrations. However, caffeine has been reported to often cause changes in membrane potential due to NCX-generated inward current, which compromises the reliability of its use. In the present study, we estimated integrated Ca2+ fluxes carried by SR-A, NCX and slow mechanisms during twitch... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Myocardium; Relaxation; Calcium fluxes; Sodium-calcium exchanger; Sarcoplasmic reticulum calcium ATPase; Caffeine. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001200014 |
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| REIS,L.A.C.; CARVALHO,F.P.; FRANÇA,A.C.; FRANCINO,D.M.T.; PINTO,N.A.V.D.; FREITAS,A.F.. |
| ABSTRACT: The most widely used herbicide in coffee crop is glyphosate, it inhibits the biosynthesis of secondary metabolites, responsible for structures and substances of plant defense. This work aimed to evaluate the morphoanatomy, total phenols, flavonoids and caffeine in leaves of Arabica coffee submitted to different sub-doses of glyphosate. The treatments were combinations of three coffee cultivars (MGS Travessia, Oeiras MG 6851 and Catuaí IAC 144) and five sub-doses of glyphosate (0.0, 57.6, 115.2, 230.4 and 460.8 g a.e. ha-1). The total thickness of the leaf blade, thickness of adaxial and abaxial epidermis, palisade and spongy parenchyma, in addition to the total phenol, total flavonoids and caffeine were evaluated 30 days after spraying. Catuaí... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Herbicide drift; Coffea arabica; Epidermis; Parenchyma; Caffeine; Flavonoid. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582018000100336 |
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| Ashihara,Hiroshi. |
| Coffee beans contain two types of alkaloids, caffeine and trigonelline, as major components. This review describes the distribution and metabolism of these compounds. Caffeine is synthesised from xanthosine derived from purine nucleotides. The major biosynthetic route is xanthosine -> 7-methylxanthosine -> 7-methylxanthine -> theobromine -> caffeine. Degradation activity of caffeine in coffee plants is very low, but catabolism of theophylline is always present. Theophylline is converted to xanthine, and then enters the conventional purine degradation pathway. A recent development in caffeine research is the successful cloning of genes of N-methyltransferases and characterization of recombinant proteins of these genes. Possible biotechnological... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coffea; Caffeine; Purine alkaloids; Pyridine alkaloids; Theobromine; Trigonelline. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202006000100001 |
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| Freire,Thamires Batello; Dario,Michelli Ferrera; Mendes,Otávio Gil; Oliveira,Andressa Costa de; Vetore Neto,Alberto; Faria,Dalva Lucia Araújo de; Silva,Vânia Rodrigues Leite e; Baby,André Rolim; Velasco,Maria Valéria Robles. |
| The Ginoide Hydrolipodystrophy (GHLD), commonly known as cellulite, occurs in 80-90% of the female population after the puberty period and comes from a metabolic modification in the cutaneous adipose tissue. Caffeine has been used in topical formulations due to its lipolytic action. We studied a nanoemulsion (F3) containing caffeine with two surfactants (oleth-3 and oleth-20) by emulsification method by phase inversion temperature inversion (PIT). The polydispersion indices (PDI) showed the reduced deviation of 0.1. The mean droplet size was ~ 40 nm. The evaluated constant of Ostwald, in the refrigerator condition was the most favorable during the stability test. In the In Raman spectroscopy assay, the caffeine bands found in F3 were compatible with those... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cellulite; Caffeine; Gynoid hydrolipodystrophy; Nanoemulsion; Permeation. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100567 |
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| Kasabova-Angelova,Alexandra; Kondeva-Burdina,Magdalena; Mitkov,Javor; Georgieva,Maya; Tzankova,Virginia; Zlatkov,Alexander. |
| The effects of new derivatives of caffeine-8-thioglycolic acid (100 µM) on isolated rat brain synaptosomes, human neuroblastoma cell line SH-SY5Y and human recombinant MAOB enzyme (hMAOB) (1 µM) were evaluated. Most of the compounds, administered alone, didn’t show statistically significant neurotoxic effects on SH-SY5Y, when compared to the control (non-treated cells). Of all studied structures JTA-2Ox, JTA-11, JTA-12 and JTA-13 decreased cell viability. In combination with 6-hydroxydopamine (6-OHDA) (100 µM), only JTA-1 and JTA-2 revealed neuroprotective effects, stronger than those of caffeine. All compounds administered alone revealed, neurotoxic effects on synaptosomes, as compared to non-treated synaptosomes. JTA-1, JTA-2 and JTA-3 showed lowest... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neuroprotection; Caffeine; Synaptosomes; SH-SY5Y; HMAOB. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100529 |
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| Leite,Paula Bacelar; Maciel,Leonardo Fonseca; Opretzka,Luiza Carolina França; Soares,Sergio Eduardo; Bispo,Eliete da Silva. |
| The "witch broom disease" caused by the fungus called Moniliophthora perniciosa is one of the most important cocoa diseases in Latin America, causing around 70% production reduction in the southern Bahia. In attempt to solve the problem, many cultivars resistant to the disease have been recommended to farmers. On the other hand, the chocolate flavour is composed by many compounds whose formation depends on the genetic background, environment where cocoa is grown and processing operations. Therefore, this work aimed at determining the monomeric phenolic compounds, methylxanthines and antioxidant activity of cocoa mass and dark chocolate from cocoa cultivars resistant to "witch broom disease" and non resistant to the disease. The total phenolic compounds in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Functional food; Theobromine; Caffeine; Epicatechin; Catechin. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542013000300007 |
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| Cardozo Junior,Euclides Lara; Donaduzzi,Carmen Maria; Ferrarese-Filho,Osvaldo; Friedrich,Juliana Cristhina; Gonela,Adriana; Sturion,José Alfredo. |
| The objective of this work was to determine the contents of methylxanthines, caffeine and theobromine, and phenolic compounds, chlorogenic and caffeic acids, in 51 mate progenies (half-sib families) and estimate the heritability of genetic parameters. Mate progenies were from five Brazilian municipalities: Pinhão, Ivaí, Barão de Cotegipe, Quedas do Iguaçu, and Cascavel. The progenies were grown in the Ivaí locality. The contents of the compounds were obtained by high performance liquid chromatography (HPLC). The estimation of genetic parameters by the restricted maximum likelihood (REML) and the prediction of genotypic values via best linear unbiased prediction (BLUP) were obtained by the Selegen - REML/BLUP software. Caffeine (0.248-1.663%) and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ilex paraguariensis; Caffeine; Caffeic acid; Chlorogenic acid; Genetic parameters; Theobromine. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2010000200008 |
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| Marcelain,Katherine; de la Torre,Consuelo; González,Patricio; Pincheira,Juana. |
| Checkpoint response to DNA damage involves the activation of DNA repair and G2 lengthening subpathways. The roles of nibrin (NBS1) and the ATM/ATR kinases in the G2 DNA damage checkpoint, evoked by endogenous and radio-induced DNA damage, were analyzed in control, A-T and NBS lymphoblast cell lines. Short-term responses to G2 treatments were evaluated by recording changes in the yield of chromosomal aberrations in the ensuing mitosis, due to G2 checkpoint adaptation, and also in the duration of G2 itself. The role of ATM/ATR in the G2 checkpoint pathway repairing chromosomal aberrations was unveiled by caffeine inhibition of both kinases in G2. In the control cell lines, nibrin and ATM cooperated to provide optimum G2 repair for endogenous DNA damage. In... |
| Tipo: Journal article |
Palavras-chave: Ataxia-telangiectasia; ATM; ATR kinases; Caffeine; G2 checkpoint; Nibrin (Nbs1); Nijmegen breakage syndrome (NBS). |
| Ano: 2005 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000200007 |
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| Bührer,Nilton E.. |
| In this work the author puts in evidence a practical and at the same time rapid method for the determination of the cafein quantity in erva-mate, that may be utilized to perfection in food and industrial analyses or others that not demand scientific rigour. The author presents a description of the method and makes a comparison with the classical method of Grandval-Lajoux, showing that the differences between the one and the other are practically nil. In conclusion, the result of the three analyses of the same sample of erva-mate, made by the Grandval-Lajoux method are cited, show that the same differences appear as those shown between the rapid method suggested by the author and the classical method. In this case, the maximum difference was 0,06% and the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Caffeine; Erva-mate; Caffeine assay. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132001000500007 |
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| Registros recuperados: 43 | |
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